Reaching fertility, an antibiotic treatment solves the problem of an infertile couple: A case report.


Authors

DOI:

https://doi.org/10.22517/25395203.24927

Keywords:

Male infertility, Bacteriospermia, Semen, Microbiota, Fertility

Abstract

The presence of bacteria in semen -bacteriospermia- is a pathological condition associated with infertility, which presentsa prevalence of up to 35%. We describe the successful management during infertility consultation of a patient suffering from oligoasthenozoospermia.

A 33-year-old male patient with a history of difficulty conceiving, a history of orchiectomy due to testicular torsion at 16 years of age, and Chlamydia trachomatis infection at 20 years of age. The physical examination showed normal results, and testicular Doppler ultrasonography presented mild left varicocele. The semen analysis reportedoligoasthenozoospermia, positive semen culture on blood agar for Streptococcus spp, and positive chocolate agar for Streptococcus spp. The treatment started with ampicillin-sulbactam administration for 14 days and a check-up after three months with a new semen analysis which showed an improved concentration and progressive sperm motility. Finally, the couple achieved a successful pregnancy.

Bacterial colonization of semen contributes to seminal quality alterations; therefore, determining bacteria's presence in infertile couples could help improve seminal parameters and achieve a successful pregnancy.

Downloads

Download data is not yet available.

Author Biographies

Ginna Marcela Ocampo Flórez, Md., Universidad CES

Médica

Especialista en urología

Esteban Calle Correa, Md., Clínica SOMA – Clínica de oncología Astorga

Médico

Especialista en urología

Alejandro Carvajal Obando, Md., Universidad CES

Médico

Profesor, Universidad CES

Walter Darío Cardona Maya, MSc. PhD., Grupo Reproducción, Facultad de Medicina, Universidad de Antioquia

Bacteriólogo

Magíster en Ciencias básicas

Doctor en Biología

 

References

Kumar N, Singh AK. Trends of male factor infertility, an important cause of infertility: A review of literature. J Hum Reprod Sci. 2015;8(4):191-6. DOI: 10.4103/0974-1208.170370

Vilvanathan S, Kandasamy B, Jayachandran AL, Sathiyanarayanan S, Tanjore Singaravelu V, Krishnamurthy V, et al. Bacteriospermia and Its Impact on Basic Semen Parameters among Infertile Men. Interdiscip Perspect Infect Dis. 2016;2016:2614692. DOI: 10.1155/2016/2614692

Baud D, Pattaroni C, Vulliemoz N, Castella V, Marsland BJ, Stojanov M. Sperm Microbiota and Its Impact on Semen Parameters. Front Microbiol. 2019;10:234.DOI: 10.3389/fmicb.2019.00234

A. Cano-Chaves, S. Galarzo-Pardo, J. Puerta-Suarez, M. Giraldo, A.P. Cadavid, W.D. Cardona-Maya. Efecto de las bacterias uropatógenas y de los factores solubles de su metabolismo sobre la calidad espermática: Escherichia coli y Enterococcus faecalis. Clínica e Investigación en Ginecología y Obstetricia. 2017; 44 (3): 106-112. DOI: 10.1016/j.gine.2015.11.005

Zeyad A, Hamad M, Amor H, Hammadeh ME. Relationships between bacteriospermia, DNA integrity, nuclear protamine alteration, sperm quality and ICSI outcome. Reprod Biol. 2018;18(1):115-21. DOI: 10.1016/j.repbio.2018.01.010

Nasrallah Y, Anani M, Omar H, Hashem A. Microbiological profiles of semen culture in male infertility. Hum Androl. 2018;8(2):34-42.DOI: 10.21608/ha.2018.3207.1023

Makler A, Urbach Y, Lefler E, Merzbach D. Factors affecting sperm motility. VI. Sperm viability under the influence of bacterial growth in human ejaculates. Fertil Steril. 1981;35(6):666-70. DOI: 10.1016/s0015-0282(16)45562-7

Moretti E, Capitani S, Figura N, Pammolli A, Federico MG, Giannerini V, et al. The presence of bacteria species in semen and sperm quality. J Assist Reprod Genet. enero de 2009;26(1):47-56. doi: 10.1007/s10815-008-9283-5

Rajasekaran M, Hellstrom WJ, Naz RK, Sikka SC. Oxidative stress and interleukins in seminal plasma during leukocytospermia. Fertil Steril. 1995;64(1):166-71.

Skau PA, Folstad I. Do bacterial infections cause reduced ejaculate quality? A meta-analysis of antibiotic treatment of male infertility. Behav Ecol. 1 de enero de 2003;14(1):40-7.https://doi.org/10.1093/beheco/14.1.40

Baker HW, Straffon WG, McGowan MP, Burger HG, de Kretser DM, Hudson B. A controlled trial of the use of erythromycin for men with asthenospermia. Int J Androl. 1984;7(5):383-8. DOI: 10.1111/j.1365-2605.1984.tb00795.x

Downloads

Published

2022-02-14 — Updated on 2022-09-17

Versions

How to Cite

Ocampo Flórez, G. M., Calle Correa, E., Carvajal Obando, A., & Cardona Maya, W. D. (2022). Reaching fertility, an antibiotic treatment solves the problem of an infertile couple: A case report. Revista Médica De Risaralda, 28(1). https://doi.org/10.22517/25395203.24927 (Original work published February 14, 2022)