Association between social determinants of health and drug-resistant tuberculosis in patients with HIV/TB coinfection in Risaralda (2016-2021)


Authors

DOI:

https://doi.org/10.22517/25395203.25687

Keywords:

Human Immunodeficiency Virus , Tuberculosis , Social Determinants of Health, Coinfection

Abstract

Co-infection of HIV and drug-resistant tuberculosis is a severe chronic infectious disease caused by *Mycobacterium tuberculosis* in people living with HIV. The department of Risaralda reported 3.03% of 344 cases at the national level, ranking in twelfth place. Identifying the social determinants of health associated with this co-infection in Risaralda will allow for more effective interventions and efficient allocation of resources.

Objective: To establish the association between social determinants of health and the presence of HIV and drug-resistant tuberculosis co-infection in Risaralda between the years 2016 and 2021.

Materials and Methods: A cross-sectional analytical study was conducted using data from the Public Health Information System (SISAP) of the department of Risaralda, during the period 2016-2021, on patients with HIV/TB co-infection and drug-resistant tuberculosis. A total of 684 records were analyzed through univariate and bivariate analysis to determine the distribution of variables, using the Chi-Square test to explore the association between drug-resistant tuberculosis and independent variables. Variables with a p-value <0.05 were considered statistically significant. The data were recorded in Excel and analyzed in SPSS version 23.

Results: Most patients were adult men from urban areas. Pulmonary tuberculosis cases were predominant, and drug resistance was significantly associated with the admission condition. Additionally, municipalities with higher levels of poverty and unmet basic needs had elevated rates of co-infection and drug resistance. No significant associations were found with other social determinants such as gender or comorbidities.

Conclusions: The condition of admission is a key determinant of TB resistance in co-infected patients. Structural determinants such as poverty did not show statistical significance, but their influence on the survival of the co-infected population was evident, highlighting the need to address socioeconomic determinants to improve clinical outcomes in these vulnerable populations.

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Published

2025-06-05

How to Cite

Salinas López, C. D., Vega Cardozo, L. D. ., Maya Diaz, J. M., Rincon-Hurtado, A.-M., & Soler Hernández , M. del P. (2025). Association between social determinants of health and drug-resistant tuberculosis in patients with HIV/TB coinfection in Risaralda (2016-2021). Revista Médica De Risaralda, 31(1), 11–30. https://doi.org/10.22517/25395203.25687

Issue

Vol. 31 No. 1 (2025): Enero-junio 2025

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Original Article

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