This is an outdated version published on 2022-08-24. Read the most recent version.

COVID-19 conditions, manifestations, and neurological repercussions


Authors

DOI:

https://doi.org/10.22517/25395203.24928

Keywords:

SARS-CoV-2, Infection, Nervous system, Pathophysiology, Pandemic

Abstract

Introduction: Severe Acute Respiratory Syndrome (SARS-CoV-2) is the pathological entity responsible for the current pandemic that not only generates a distinctive respiratory pattern but has also been associated with multiple mechanisms of invasion of the central nervous system (CNS).

Objective: To determine the affections, manifestations and neurological repercussions that SARS-CoV-2 infection can generate.

Methods:  Review of the scientific literature of patients with SARS-CoV-2 infection, in whom the development of conditions, manifestations and neurological repercussions, selected outcome in the studies, presence of micro and macroscopic conditions of the CNS and peripheral (PNS) were evaluated.

Results: 40 articles were included where the family and structure of SARS-CoV-2, pathophysiological mechanisms, neurological clinical manifestations, and possible repercussions at the central nervous system level were analyzed.

Conclusions: SARS-CoV-2 is a pathological entity that is associated with different mechanisms of neurological intervention, through direct infection to the CNS, secondary to a parainfectious and postinfectious process, related to cytokine storm syndrome, endothelial damage, thrombotic disorders, in addition to secondary to hypoxia, hypoxemia and multiple organ failure.

Downloads

Download data is not yet available.

Author Biographies

Benjamín Alexánder Márquez Rosales, Md. Mg, Hospital Universitario San Rafael de Tunja

Médico

Especialista en neurología

Especialista en medicina familiar

Magíster en enfermedades infecciosas

Ledmar Jovanny Vargas Rodríguez, Md., Hospital Universitario San Rafael. Universidad de Boyacá

Médico

Especialista en Epidemiología

Sonia Elizabeth Reyes Peña, Md., Hospital Universitario San Rafael. Universidad de Boyacá

Médica

Especialista en Epidemiología

Luisa Ivonne Guerra Guerra, Universidad de Boyacá

Estudiante de medicina. Universidad de Boyacá.

Diana Paola Sanabria Aguilar, Universidad de Boyacá

Estudiante de medicina. Universidad de Boyacá

Downloads

Published

2022-02-14 — Updated on 2022-08-24

Versions

How to Cite

Márquez Rosales, B. A., Vargas Rodríguez, L. J., Reyes Peña, S. E., Guerra Guerra, L. I., & Sanabria Aguilar, D. P. (2022). COVID-19 conditions, manifestations, and neurological repercussions. Revista Médica De Risaralda, 28(1). https://doi.org/10.22517/25395203.24928 (Original work published February 14, 2022)